Analyses of craniofacial and dental morphology in monozygotic twins discordant for cleft lip and unilateral cleft lip and palate
The Michigan Cleft Twin Sample data was analyzed in order to investigate dental arch and craniofacial morphology. The present study consisted of 12 monozygotic twins discordant for either cleft lip or unilateral cleft lip and palate. Individuals having CL (repaired) alone did not differ from their unaffected counterparts in dental arch and skeletal morphology. Repaired UCLP subjects were characterized by having a shorter and more posteriorly positioned maxilla. Although reduction of dental arch width as a result of scar contraction following surgery was evident, the effects of scar tissue pull did not affect maxillary basal width.Abstract
Contributor Notes
C-A. Trotman is an Assistant Professor in the Department of Orthodontics and Pediatric Dentistry at the University of Michigan, Ann Arbor, Michigan
A.R. Collett is a Visiting Research Fellow at the Department of Orthodontics and Pediatric Dentistry, University of Michigan, Ann Arbor, Michigan
J.A. McNamara, Jr. is a Professor in the Department of Orthodontics and Pediatric Dentistry, and a Research Scientist at the Center for Human Growth and Development, University of Michigan, Ann Arbor, Michigan
S.R. Cohen is an Assistant Professor in the Section of Plastic Surgery, and Director of the Craniofacial Anomalies Program at the University of Michigan, Ann Arbor, Michigan